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KMID : 0357919870210030185
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Korean Journal of Pathology
1987 Volume.21 No. 3 p.185 ~ p.191
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Secondary Biliary Cirrhosis in A Case with Intraductal Growth of Hepatocellular Carcinoma
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Abstract
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A case of hepatocellular carcinoma(HCC) complicating with secondary biliary cirrhosis
due to intrahepatic bile dugs growth of the tumor is presented.
The patient was a 34 year-old male who had been suffered from right upper quadrant
pain with intermittent fluctuating jaundice for 4 months. Left lobectomy specimen
contained a single, 4 cm sized, relatively well circumscribed and partly protruding
nodular HCC in the medial spement of left lobe. It compressed the left hepatic duct, and
the intra and extra-hepatic ducts were completely plugged with tumor casts (extending
to the common bile duct at the operating table). Remaining hepatic parenclyma was the
seat of advanced secondary biliary cirrhosis in which were abundance of
HBsAg-containing hepatocytes possibily representing a HBsAg carrier status. Biliary
cirrhosis in HCC is an extremely rare manifestation, reflecting the delayed adequate
clinical procedure by unusual pattern of obstructive jaundice. In such a case presenting
as persisting and fluctuating obstructive jaundice in HCC, an intrabile duct tumor
growth should be suspected.
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